Summary of Recommendations and Evidence
| Population |
Recommendation |
Grade
(What's This?) |
| Asymptomatic Adults |
The USPSTF recommends against routine screening for pancreatic cancer in asymptomatic adults using abdominal palpation, ultrasonography, or serologic markers.
|
D |
The USPSTF found no evidence that screening for pancreatic cancer is
effective in reducing mortality. There is a potential for significant
harm due to the very low prevalence of pancreatic cancer, limited
accuracy of available screening tests, the invasive nature of diagnostic
tests, and the poor outcomes of treatment. As a result, the USPSTF
concluded that the harms of screening for pancreatic cancer exceed any
potential benefits.
- Due to the poor prognosis of those diagnosed with pancreatic
cancer, there is an interest in primary prevention. The evidence for
diet-based prevention of pancreatic cancer is limited and conflicting.
Some experts recommend lifestyle changes that may help to prevent
pancreatic cancer, such as stopping the use of tobacco products,
moderating alcohol intake, and eating a balanced diet with sufficient
fruit and vegetables.
- Persons with hereditary pancreatitis may have a higher lifetime risk for developing pancreatic cancer.4 However, the USPSTF did not review the effectiveness of screening these patients.