connective-tissue-disorder : Symptoms, Causes, Treatment & Prevention

What is Connective Tissue Disorder?

A connective tissue disease is any disease that affects the parts of the body that connect the structures of the body together. Connective tissues are made up of two proteins: collagen and elastin. Collagen is a protein found in the tendons, ligaments, skin, cornea, cartilage, bone, and blood vessels.

What are the causes of Connective Tissue Disorder?

The specific causes of most connective tissue diseases are not known. However, there are genetic patterns that are considered to increase the risk for developing connective tissue diseases. It is likely that a combination of genetic risks and environmental factors are necessary for the development of connective tissue disease.

What are the symptoms of Connective Tissue Disorder?

A common symptom of a connective tissue disease is nonspecific fatigue. Depending on which connective tissue disease is present, and how active it is, a wide variety of symptoms may occur. These include fevers, muscle and joint pain and stiffness, weakness, and many other symptoms.

How is Connective Tissue Disorder diagnosed?

The doctor can sometimes detect a connective tissue disease simply by the physical examination. Blood testing, X-ray examination, and other tests can help in making a diagnosis of connective tissue disease.

What are the treatments of Connective Tissue Disorder?

Corticosteroids are usually effective, especially when the disease is diagnosed early. Mild cases can be treated with nonsteroidal anti-inflammatory drugs (NSAIDs), hydroxychloroquine or similar drugs, or very low doses of corticosteroids. The more severe the disease, the higher the dose of corticosteroid needed. In severe cases, immunosuppressive drugs (such as azathioprine, methotrexate, or cyclophosphamide) may also be needed.